KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NCL
All Species:
30
Human Site:
T498
Identified Species:
66
UniProt:
P19338
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19338
NP_005372.2
710
76614
T498
S
N
L
S
Y
S
A
T
E
E
T
L
Q
E
V
Chimpanzee
Pan troglodytes
XP_516145
1006
108719
T770
S
S
A
Y
V
R
T
T
S
R
T
L
Q
H
V
Rhesus Macaque
Macaca mulatta
XP_001116949
938
100743
T726
S
N
L
S
Y
S
A
T
E
E
T
L
Q
E
V
Dog
Lupus familis
XP_850477
699
75739
T487
S
N
L
S
Y
S
A
T
E
E
T
L
Q
E
V
Cat
Felis silvestris
Mouse
Mus musculus
P09405
707
76705
T499
S
N
L
S
Y
S
A
T
K
E
T
L
E
E
V
Rat
Rattus norvegicus
P13383
713
77129
T501
S
N
L
S
Y
S
A
T
E
E
T
L
Q
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509329
631
67414
T441
N
N
L
A
Y
S
A
T
E
E
G
L
Q
E
V
Chicken
Gallus gallus
P15771
694
75622
S473
N
N
L
S
Y
A
A
S
E
E
T
L
Q
E
L
Frog
Xenopus laevis
P20397
651
70177
L431
Y
S
A
T
E
D
S
L
R
E
V
F
E
K
A
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797746
400
43419
T253
P
K
A
N
G
D
S
T
P
A
P
A
N
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P27476
414
44517
D267
D
T
P
S
E
P
S
D
T
L
F
L
G
N
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.3
74.7
91.6
N.A.
83.9
84.2
N.A.
65.6
63.2
55.6
N.A.
N.A.
N.A.
N.A.
N.A.
24
Protein Similarity:
100
70.4
75.4
94.9
N.A.
90.1
90.4
N.A.
73.9
76
68.4
N.A.
N.A.
N.A.
N.A.
N.A.
32.8
P-Site Identity:
100
40
100
100
N.A.
86.6
100
N.A.
80
73.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
46.6
100
100
N.A.
100
100
N.A.
93.3
100
40
N.A.
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
28
10
0
10
64
0
0
10
0
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
19
0
10
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
19
0
0
0
55
73
0
0
19
64
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
0
10
0
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
10
0
0
0
0
10
0
% K
% Leu:
0
0
64
0
0
0
0
10
0
10
0
82
0
0
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
19
64
0
10
0
0
0
0
0
0
0
0
10
10
0
% N
% Pro:
10
0
10
0
0
10
0
0
10
0
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
64
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
10
10
0
0
0
0
0
% R
% Ser:
55
19
0
64
0
55
28
10
10
0
0
0
0
0
10
% S
% Thr:
0
10
0
10
0
0
10
73
10
0
64
0
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
64
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
10
64
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _